Ipamorelin CAS: 170851-70-4 IPAMORELIN;AIB-HIS-D-NAL(2)-D-PHE-LYS-NH2
Usage
Ipamorelin (INN) (development code NNC 26-0161) inonzi peptide-selective agonist yeauxin inobudisa peptides/somatosecretin receptors (GHS) uye somatosecretin.Iyo pentapeptide ine amino acid sequence Aib-His-D-2-Nal - D-Phe -Lys-NH 2, yakabva kuGHRP-1.
Ipamorelin inonyanya kuwedzera plasma kukura hormone (GH) mazinga mumhuka uye vanhu.Mukuwedzera, ipamorelin yakakurudzira kuwedzera uremu mumhuka.Kufanana nepralmorelin uye GHRP-6, ipamorelin haibatsiri prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), kana thyrotropin (TSH) mazinga.Zvisinei, kusiyana nepramoline (GHRP-2) uye GHRP-6, asi yakafanana nekukura kwehomoni kubudisa hormone (GHRH), iparerelin haina kukurudzira kuvharwa kwe adrenocorticotropic hormone (ACTH) kana cortisol uye inonyanya kusarudzwa pakukonzera GH secretion chete.
Ipamorelin yakatanga kugadzirwa neNovo Nordisk uye yakaitisa chikamu chechipiri chekliniki miedzo pachayo semushonga we postoperative ilobstruction, asi yakabviswa nekuda kwekushaya simba.
Ipamorelin yakashandiswa nevatambi semushonga unosimudzira.