Inhibitor GW0742 CAS 317318-84-6 White powder

Andarine (S-4) ndiyo yakagadzirwa nearylpropionamide [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] kutanga inotsanangurwa naYin et al.kuve yakasarudzika androgen receptor modulator (SARM).Andarine (S-4) yakaratidzwa ne in vitro uye in vivo zvidzidzo kuti ive inoshanda anabolic agonist, isina side-effects inowanzobatanidzwa nevanabolic-androgenic steroids, ine chokuita zvikuru ne substrate affinity ye 5α-reductase kuti ibudise DHT muprostate.
Chiitiko chemishonga che andarine chinoratidza kukwanisa kukuru kwe andarine mukugadzirwa kweSARMs inowanikwa muchipatara, iyo inopa zvakasiyana-siyana zvekurapa pamusoro pevamwe vavo ve steroidal uye mukana unonakidza wekugadzirisa zvakasiyana-siyana migumisiro ye androgen mumhando dzakasiyana-siyana dzakanangwa, nokudaro kuderedza kupindira kune zvakajairwa. .Nekudaro, andarine ine chivimbiso chepamusoro chekiriniki miedzo inovavarira kurapa zvirwere zvine hukama nezera uye kurwisa zviratidzo zvezvirwere zvakakomba senge sarcopenia uye cancer cachexia.
Andarine inosarudza nonsteroidal androgen receptor (AR) agonist ine Ki ye4 nM.Andarine inoratidzira ine simba uye inoshanda anabolic chiitiko uye inoguma nedosi-inotsamira kukurudzira kwekukura muprostate, seminal vesicles, zvichiteerana.Andarine ine zvinogona antiosteoporotic properties.
Andarine (yaimbozivikanwa seGTx-007; S-4; GTx007; S4) ndeyemuromo bioactive uye inosarudza isiri-steroidal androgen receptor (AR) agonist, kunyanya inosarudza androgen receptor modulator (SARM), inogona kubatsira mukuparadza tsandanyama. uye osteoporosis.Inomutsa AR neKi ye4 nM uye inosarudza tishu-yenhengo dzeanabolic.Andarine iri kuferefetwa yekurapa zvirwere zvakaita sekutambisa tsandanyama, osteoporosis uye benign prostatic hypertrophy.Mumuenzaniso wemhuka webenign prostatic hypertrophy, andarine yakaratidzwa kuderedza uremu hweprostate nekubudirira kwakafanana kune finasteride, asi pasina kuburitsa chero kuderedzwa kwemhasuru kana anti-androgenic mhedzisiro.